Why are protein so fragile

Answers

Answer 1
Levels of selective constraint vary among proteins. Although strong constraint on a protein is often attributed to its functional importance, evolutionary rate may also be limited if a protein is fragile, such that a large proportion of amino acid replacements reduce its fitness. To determine the relative contributions of essentiality and fragility to selective constraint, we compared relationships of selection against nonsense mutations (snon) and selection against missense mutations (smis) to protein sequence conservation (Ka).

Related Questions

Los elefantes marinos del norte tienen poca variabilidad genética, probablemente, por un proceso que le hicieron pasar los hombres en la década de 1890. La caza hizo disminuir el censo poblacional hasta tan sólo 20 individuos a finales del siglo XIX. Desde entonces, su población ha «rebotado» hasta más de 30 000, pero sus genes todavía llevan las señales de sus aquellas generaciones su variabilidad genética es mucho menor que la de una población de elefantes marinos del sur que no sufrió una caza tan intensa. Este proceso puede denominarse como:


Seleccione una:
Cuello de botella
Especiación
Selección natural
Efecto fundadorLos elefantes marinos del norte tienen poca variabilidad genética, probablemente, por un proceso que le hicieron pasar los hombres en la década de 1890. La caza hizo disminuir el censo poblacional hasta tan sólo 20 individuos a finales del siglo XIX. Desde entonces, su población ha «rebotado» hasta más de 30 000, pero sus genes todavía llevan las señales de sus aquellas generaciones su variabilidad genética es mucho menor que la de una población de elefantes marinos del sur que no sufrió una caza tan intensa. Este proceso puede denominarse como:


Seleccione una:
Cuello de botella
Especiación
Selección natural
Efecto fundador

Answers

Answer:

elefantes marinos mmmmmmmmmm

The total acreage destroyed by the gypsy moth is in the
hundreds.
thousands.
millions.
billions.

Answers

Answer:

millions

Explanation:

how many sperm cells are formed from an original cell in a drosophila fruit fly at the conclusion of meiosis.

Answers

Answer:

Four sperm cells

Explanation:

Use Darwin's theory of Natural Selection to explain the process by which the four-legged land animal, A, may have evolved, over about 20 million years, from the fish-like creature, C, in the swampy conditions of the time.

Answers

Answer:

Due to environmental conditions.

Explanation:

With the passage of time, environmental conditions change which causes the evolution of of four legged land animals from fish like creature. This change occurs due to change in environment. In water, there is no need for legs because fish moves with the help of fins and tail but the organisms that lives on land has legs in order to move from one place to another so we can say that change in the physical structure of organism occurs due to environment.

Removal of trees causes more erosion and sedimentation
True
or
False

Answers

True! The roots help anchor the soil together slowing down and preventing erosion
Yo WaSsuPp!!   ^v0!!

                       "Removal of trees causes more erosion and sedimentation

True

or

False"

  Well the question are getting easier by the minute-..

((-Side Note-)): Trees keep the dirt and grass in place with their roots, it's kinda like an anchor, removing the trees means the the dirt will be loose and it will be easy for the dirt to be washed or blown away but water and wind!

SO! with that being said the answer is!TRUE!!                   I apologize if i'm wrong // Your welcome if i'm correctand           ((-Credit to Hona-Chan-))Here's a picture that might make ur day better ^v^!!∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨∨

PLZ HELP!
What did the Fish and Wildlife Service (FWS) do to bring back black-footed ferrets from extinction?
The captive breeding program was implemented too late to save the black-footed ferret.
The FWS moved mating pairs from the Wyoming population to over 8 western states and Mexico to begin new colonies.
The FWS use a captive breeding program to start populations in 8 states.
The FWS monitored a Wyoming population and captured enough individuals to start new populations.

Answers

Answer:

The FWS use a captive breeding program to start populations in 8 states.

Explanation:

this is correct i got it right

HELP ME PLEASEE!!! I WILL NAME YOU BRAINLIEST!!!

based on the graph below, from 1900 to 2000, humas have been experiencing what type of population growth?

A) Stagant
B) Logistic
C) Continuous
D) Exponential

Answers

Answer:

Exponential

Explanation:

reference the shape of the graph

Can someone help me if this is correct

Answers

Answer:

It's probably correct.

as the population size gets
The growth rate tends to
closer to the carrying capacity.

Answers

Answer:

As population size approaches the carrying capacity of the environment, the intensity of density-dependent factors increases. For example, competition for resources, predation, and rates of infection increase with population density and can eventually limit population size.

Explanation:

Hope this helps! ^_^

Which of the following could be present in a prokaryotic cell? *
Ribosomes
Cell Wall
Cell Membrane
Nucleus
Membrane-Bound Organelles
DNA

Answers

Cell wall Prokaryotes are single-celled organisms belonging to the domains Bacteria and Archaea. Prokaryotic cells are much smaller than eukaryotic cells, have no nucleus, and lack organelles. All prokaryotic cells are encased by a cell wall.

Answer:

they actually do not have a nucleas

Interferons Interferons reduce macrophage chemotaxis to the infection. interfere with viral replication. prevent viruses from entering a cell. bind to viruses and destroy them. prevent viruses from leaving a cell.

Answers

Answer:

interfere with viral replication

Explanation:

Interferons (IFNs) are proteinous molecules, which are part of the innate immune system of our body. Interferons are produced in response to viral infections and they often specialize in preventing the virus pathogen from replicating or multiplying in the host cell.

As their name implies, INTERFERONS interfere with the replication of viral pathogens, hence, preventing the virus from further invading the host cell. This is done at the innate immunity level.

what are three types of muscle tissues in the human body and where are they located

Answers

cardiac, smooth, and skeletal.

Hopes this helps:

Answer: Cardiac, Smooth, and Skeletal.

The three types of muscle tissue are cardiac, smooth, and skeletal. Cardiac muscle cells are located in the walls of the heart. Smooth muscle fibers are located in walls of hollow visceral organs. Skeletal muscle fibers are located in muscles.

In humans, colorblindness is a recessive, sex-linked trait. What is the probability
that the children of a woman heterozygous for colorblindness and a man with
normal color vision will be colorblind?

Answers

Explanation:

Taking Xx as heterozygous and XX for normal

Woman =Xx Man =XX

all possible outcomes are XX, XX, XX and Xx

there is 0 probability of having a colorblind child

(But there is a 25 % chance that the child may be a carrier like its mother)

Pls answer this question 18

Answers

Answer: i belive a. mark brainlyest if corest plz ;P

Explanation:

do not have any particular arrangement and there are very, very weak forces between them. So, the particles in a gas can easily move around and fill the shape of the container they are in, meaning they have no fixed shape.

A.) far apart and freely moving

In what form is the DNA found when a cell is beginning cell division or is involved in cell division?
A.) Centromere
B.) Chromosome
C.) Chromatin

Answers

DNA is usually in chromatin form

3 ideas that an individual person can do to help. With air pollution?

Answers

Answer:

Reduce the number of trips you take in your car. Reduce or eliminate fireplace and wood stove use. Avoid burning leaves, trash, and other materials. Avoid using gas-powered lawn and garden equipment.

Explanation:

Ima different breed

Do new trees provide the same resources for animals in the forest as adult trees do?

Answers

Answer:Yes, trees release oxygen and some produce food for the animals weather there young or old

Explanation:

Yes they take in Carbon Dioxide to help us

What is the resulting mRNA? 1.AUU-GAG-CAU-CAA-AAU-CCG 2.UAA-CUC-GUA-GUU-UUA-GGC 3.TAA-CTC-GTA-GTT-TTA-GGO
4.None of the above​

Answers

Answer: 3

Explanation:

Just put 3

money feed on both plants and animals therefore man is said to be a/an​

Answers

man is said to be an animal

6. ¿Cuál de las siguientes moléculas está formada por
glicerol y ácidos grasos?

Azúcares
Almidones
Lípidos
O ácidos nucleicos

Answers

Answer:

Lípidos

Explanation:

Which item creates more than 50 decibels of sound?

Answers

If there are no multiple choice options; a refrigerator makes about the same of 50 decibel, an electric toothbrush makes about 60 and a washing machine makes 70

Un organismo que solo come plantas es un (a)

Answers

Answer:

Herbívoros

Explanation:

Son animales que se alimentan exclusivamente de plantas, pastos, hierbas y vegetales en general. Hay muchos herbívoros que comen huevos y a veces otras proteínas provenientes de animales. Ejemplos de herbívoros: caballo.

Herbivores: They are animals that eat plants,grasses,herbs and vegetables,.Examples of herbivores: cows, deer, or rabbits.

How can you check the accuracy of the results of your experiment?

1. by testing different variables
2. by assuming your results are correct
3. by completing a different experiment
4.by repeating your experiment

Answers

Answer:

I think either 1 or 4 but I think 1

Answer:

Explanation:

4 is the answer

Examine the words and/or phrases below and determine the relationship
among the majority of words/phrases.
Choose the option that does not fit the pattern.
fire
overgrazing of lands
ground cover alteration
drought

Answers

overgrazing of lands; it is the only density dependent factor

WHY SOME FAMILY MEMBERS LOOK VERY SIMILAR WHILE OTHERS LOOK VERY DIFFERENT? pleaseee :c

Answers

I actually question that too, my dad was really tall, so is my mom and my mom has straight hair, but I’m short with wavy hair, but my mom say it’s probably from my grandma who has wavy hair.

Where does the carbon comes from that makes up the glucose molecules?

Answers

Answer:

from CO2

Explanation:

Answer:

carbon dioxide

Explanation:

The carbon atoms used to build carbohydrate molecules comes from carbon dioxide, the gas that animals exhale with each breath. The Calvin cycle is the term used for the reactions of photosynthesis that use the energy stored by the light-dependent reactions to form glucose and other carbohydrate molecules

How do the nervous system and skeletomuscular system interact?

Answers

nerves send the messages that make muscles move

Wave amplitude depends on
1. wavelength
2. wave speed.
3. wave energy.
4. wave frequency.
5. wave energy of the original disturbance.


Help please!!

Answers

Wave energy. A high amplitude carries a large amount of energy and a low amplitude carries a small amount of energy.

HELP ME WITH THIS MITOSIS DIAGRAM PLEAASE

Answers

Answer: A/#1= Prophase B/#2= Metaphase C/#3= Anaphase D/#4= Telaphase

Explanation:

Can someone plz help me

Answers

Answer:

Circulatory system and Respiratory system

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